Citra-k

Citra-K®(Potassium Citrate and Citric Acid Monohydrate) Presentation Citra-K oral solution: Light yellow solution; each 5 ml oral solution contains Potassium Citrate USP 1.5 g and Citric Acid Monohydrate USP 250 mg. Indications For the symptomatic relief of dysuria associated with mild urinary tract infections, especially cystitis. Dosage and administration Adults including the elderly, and children over 6 years: 10 ml Citra-K oral solution three times daily. Citra-K oral solution should be taken diluted with one glassful of water (250 ml) followed by additional water, if desired. Childeran 1-6 years of age: 5 ml Citra-k oral solution three times daily. Citra-k oral solution should be taken diluted with half glassful of water (125 ml) followed by additional water, if desired. Shake the bottle well before use. Contra-indications, warnings, etc. Contra-indications: Potassium citrate oral solution is contra-indicated in hyperkalaemia, renal dysfunction, ventricular arrhythmics, Addison’s disease and in known hypersensitivity to potassium citrate or any other ingredient. Warnings and precautions: Potassium Citrate oral solution provides symptomatic relief only and is not an anti-bacterial. Effective anti-bacterial therapy should be co-prescribed. It should be used with caution when renal or cardiac dysfunction is present. Citrate mobilizes calcium from bones and increases its urinary excretion. This together with raised urinary pH may predispose to formation of stones in the urinary tract. This product contains 2 g of sucrose per 10 ml dose. This should be taken into account in patients with diabetes mellitus. Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine. Use in pregnancy and lactation: There are no adequate data from the use of Potassium Citrate oral solution in pregnant women. Animal studies are insufficient with respect to effects on pregnancy. The potential risk to humans is unknown. Potassium Citrate oral solution should not be used during pregnancy unless clearly necessary and on the advice of a physician. Side-effects: Mild nausea and occasionally vomiting may occur due to gastric irritation. Drug interactions: Concurrent administration of Potassium-containing or sparing medications may lead to hyperkalaemia. May interact with cardiac glycosides. Citrates alkalinize the urine and thus may alter the urinary excretion of a number of drugs. Particularly noteworthy is the diminished anti-bacterial activity of nitrofurantoin. Overdose: Overdosage is accompanied by nausea, vomiting, abdominal pain and symptoms due to hyperkalaemia and metabolic acidosis. Fluid and electrolyte balance together with ECG should be closely monitored. Treatment is symptomatic and supportive. Moderate to severe hyperkalaemia is a medical emergency requiring prompt correction. Pharmaceutical precautions Store in a cool and dry place, protected from light. Packaging quantity Citra-K oral solution: Carton containing 200 ml solution in bottle.